The VPS37A antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to VPS37A, and VPS37A subunit of ESCRT-I. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The VPS37A antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene